CDNA 3
AMD Instinct MI300X
wins
4
The AMD MI300X leads all GPUs on memory capacity (192GB HBM3) and bandwidth (5.3 TB/s), making it exceptional for serving very large language models that don't fit on H100.
Hopper
NVIDIA H100 80GB
wins
1
The NVIDIA H100 is the gold standard for AI training and inference. With 80GB HBM3 memory and NVLink 4.0 support, it dominates large-model training and multi-GPU clusters.
Performance comparison
Visual bars — winner highlighted
AMD Instinct MI300X
Metric
NVIDIA H100 80GB
FP16 TFLOPS
Bandwidth
VRAM
TDP (lower=better)
TFLOPS/watt
GB/s per watt
Full specification table
| Spec | AMD Instinct MI300X | NVIDIA H100 80GB |
|---|---|---|
| Architecture | CDNA 3 | Hopper |
| VRAM | 192 GB HBM3 | 80 GB HBM3 |
| VRAM type | HBM3 | HBM3 |
| Memory bandwidth | 5,300 GB/s | 3,350 GB/s |
| FP16 TFLOPS | 1,307 TFLOPS | 989 TFLOPS |
| TDP | 750 W | 700 W |
| TFLOPS/watt | 1.74 T/W | 1.41 T/W |
| GB/s per watt | 7.07 GB/s/W | 4.79 GB/s/W |
| NVLink | No | Yes |
| Release year | 2023 | 2022 |
Live cloud pricing
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Power efficiency analysis
TFLOPS/watt and GB/s/watt — critical for data center TCO
AMD Instinct MI300X
NVIDIA H100 80GB
TFLOPS/watt measures compute efficiency — how much AI throughput you get per watt of power consumed. For data centers with PUE of 1.2–1.5, a 10% improvement in TFLOPS/watt translates directly to lower electricity costs and cooling requirements. GB/s/watt measures memory bandwidth efficiency, which is the binding constraint for memory-bound LLM inference workloads.
When to choose each GPU
Choose AMD Instinct MI300X for:
- Memory-bound LLM inference
- Large model serving
- HPC
Choose NVIDIA H100 80GB for:
- LLM training
- Large-scale inference
- HPC workloads
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